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Nevertheless, the realm of conformation and what A part of the receptor it bonds to, as an alternative to how "tightly" or well it bonds, seems to be The explanation with the euphoria. See my thread here along with the interpretation of the info introduced:
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The DOx loved ones of psychedelics are also known as "substituted amphetamines" because they contain the amphetamine backbone but are substituted on the benzene ring. This provides increase to serotonin agonists similar to the 2C-X course but extra resistant to elimination in the human body.
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